Peyronie’s Disease is a condition that affects many men worldwide, yet it is still relatively unknown to the general public. Patients with this condition develop fibrous scar tissue in the penis, which can cause pain and curvature during an erection. Symptoms can range from mild discomfort to severe pain; in some cases, it can lead to erectile dysfunction. 

While the exact cause of Peyronie’s Disease is still unknown, doctors believe it may be linked to genetic factors, trauma to the penis, or autoimmune disorders. Fortunately, there are a variety of treatment options available that can help alleviate the symptoms of this condition.

In this article, we will explore the symptoms, causes, and treatment options for Peyronie’s Disease, so you can understand this condition better and take the necessary steps to seek treatment.

Symptoms

There are several symptoms associated with Peyronie’s Disease. The most common symptom is the development of fibrous scar tissue on the penis, which can cause a curvature of the penis during an erection. This curvature can be painful and uncomfortable; in severe cases, it can even make sexual intercourse difficult or impossible. Other symptoms of Peyronie’s Disease include:

• Pain during an erection

• Shortening of the penis

• Difficulty achieving or maintaining an erection

• Psychological distress, anxiety, or depression related to the condition

It’s important to note that the severity of these symptoms can vary from person to person. Some men may only experience mild discomfort, while others may experience more severe symptoms that significantly impact their quality of life.

Causes

The exact cause of Peyronie’s Disease is still unknown, but doctors believe it may be linked to several factors. One of the most common causes is trauma to the penis, such as during sexual activity, sports, or an accident.

Some men may also be genetically predisposed to developing Peyronie’s Disease, as it can run in families. Additionally, autoimmune disorders and other medical conditions may increase the risk of developing Peyronie’s Disease.

Diagnosis

If you are experiencing symptoms of Peyronie’s Disease, seeking medical attention from a qualified healthcare provider is essential. Your doctor will likely perform a physical examination and order imaging tests, such as an ultrasound or MRI, to confirm the diagnosis. They will also ask about your medical history and any other symptoms you may be experiencing.

Conventional Treatment Options

Several conventional treatment options for Peyronie’s Disease include medication, surgery, and medical devices. 

Medications 

• Medications, such as collagenase injections, can help break down the scar tissue in the penis and improve symptoms. 

Surgery 

• Surgery may be recommended for severe cases and involve removing the scar tissue or inserting a penile implant to straighten the penis. 

Medical Devices 

• Practitioners may recommend medical devices such as vacuum pumps to improve symptoms.

• However, these conventional treatment options may have risks and side effects, such as pain, infection, or a decreased ability to achieve or maintain an erection. Additionally, they may not be suitable for everyone, especially those with underlying medical conditions.

Lifestyle Changes to Support Regenerative Treatment for Peyronie’s Disease

In addition to regenerative treatments, several lifestyle changes can support the body’s natural healing processes and improve symptoms of Peyronie’s Disease. These include:

• Eating a healthy diet rich in vitamins and minerals

• Exercising regularly to improve blood flow to the penis

• Quitting smoking, as smoking can damage blood vessels and impede healing

• Reducing stress, as stress can exacerbate symptoms of Peyronie’s Disease

Alternative Remedies

Several alternative remedies may help alleviate symptoms of Peyronie’s Disease, although more research is needed to confirm their effectiveness. These include:

• Acupuncture

• Massage therapy

• Vitamin E supplements

• Coenzyme Q10 supplements

Platelet Rich Plasma (PRP) Therapy for Peyronie’s Disease

Platelet Rich Plasma (PRP) therapy involves injecting a concentrated solution of the patient’s platelets into the affected area of the penis. Platelets contain growth factors that can stimulate the body’s natural healing processes and promote healthy tissue growth. PRP therapy effectively reduces pain and curvature of the penis in patients with Peyronie’s Disease. 

According to research from the 2021 Sexual Medicine Society of North America Fall Scientific Meeting, PRP injections may be a safe and effective approach to treating Peyronie’s. This study was small, with only six patients, each completing two injections. But one of the authors of the study, Kevin Chu, said:

“…there were no noted adverse effects for patients that received PRP injections. We had thought there would be some patients with mild ecchymosis or penile pain. This, of course, may change as we enroll more patients into the trial and our sample size gets larger. But from a preliminary standpoint, it appears to be safe to use in patients with Peyronie’s Disease.”

A clinical trial launched at the University of Miami Miller School of Medicine compared PRP with a placebo in patients with Peyronie’s Disease. It evaluated them for complications and tolerability following their injections. The takeaway was that PRP appeared to be a safe treatment for patients with Peyronie’s Disease.

Conclusion

Peyronie’s Disease is a condition that can cause significant discomfort and impact a man’s quality of life. Fortunately, various treatment options are available, including PRP Therapy, a regenerative technique. If you’re experiencing symptoms of Peyronie’s Disease, it’s essential to seek medical attention from a qualified healthcare provider to determine the best course of treatment for you. 

Dr. Eric Cerré offers PRP Therapy for Peyronie’s Disease. Call the office to see how he can help you!